
AI-Native Startup Builder Checklist
Define the Problem (Market-First, Not Tech-First)
- Identify a high-frequency, high-cost pain point
- Validate it with real users or operators
- Confirm the problem generates or relies on large data streams
- Define what 10x better looks like with AI
Design an AI-First Architecture
- Choose where AI delivers core value (e.g. output, decision, automation)
- Map out the data flow (input → model → feedback → retrain)
- Determine model approach: LLM, CV, time series, hybrid
- Select AI infra: vector DB, LLM provider, data labeling, etc.
Assemble Your Founding Team
- ML/AI engineer with deployment experience
- Domain expert (deep industry knowledge)
- Product/UX builder to turn models into experiences
- Optional: operations or GTM expert for early growth
Secure or Generate Proprietary Data
- Identify or negotiate access to unique datasets
- Build a system to collect structured feedback from users
- Plan for data labeling (manual, synthetic, weak supervision)
- Ensure data privacy & compliance from day one
Build the First AI-Powered MVP
- Define narrow, specific use case for MVP
- Ship a functional prototype using real user data
- Include human-in-the-loop where model is uncertain
- Track usage, feedback, and accuracy from launch
Measure Value, Not Just Accuracy
- Define clear ROI metrics (e.g. time saved, errors avoided)
- Track before/after benchmarks with early users
- Use data to prove the AI is the reason for the impact
- Set goals for model improvement and value per user
Build Scalable AI-First Economics
- Keep marginal cost low as volume scales
- Automate wherever the model has >90% confidence
- Structure pricing around value delivered (not usage)
- Plan for gross margins >70% with automation at scale
Create Feedback & Training Loops
- Log every input/output/user correction
- Retrain models with updated real-world usage
- Track performance deltas across versions
- Use fine-tuning or LoRA as model improves
Prepare for Distribution
- Define who owns the problem internally (buyer persona)
- Build a demo that shows clear before/after
- Create bottom-up growth path (self-serve or pilot)
- Position as "AI-native solution," not just AI add-on
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